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ea0026p134 | Growth factors | ECE2011

Circulating insulin-like growth factor 1 (IGF1) and mortality: meta-analysis and dose-response meta-regression

Burgers A M G , Biermasz N R , Schoones J W , Pereira A M , Renehan A G , Zwahlen M , Egger M , Dekkers O M

Background: Insulin-like growth factor 1 (IGF1) plays a central role in metabolism and growth regulation. High IGF1 levels are associated with an increased risk of cancer, low IGF1 levels with increased risk for cardiovascular disease. We hypothesized that the relationship between circulating total IGF1 levels and mortality is U-shaped.Methods: We performed a systematic review searching PubMed, EMBASE, Web of Science, Cochrane Library (1985 to September ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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